 | Slime Mold Sconce | A glowy slime mold stalk mounted nicely on your wall. | Building & Utilities | |
| Slime Mold Stalk | The glowing mold found underground. Can probably be used as a light source. | Materials | 1 |
 | Slime Mold Torch | A torch-like stalk from a cluster of mold. Should be able to light your way for a short time. | Weapons | 1 |
 | Smasher | Power pulses through your limbs as you bring clubs down with unmatched intensity. Club attacks deal bonus stun. | Mutations | |
 | Smithing Station | Work station used to upgrade weapons using various materials. | Building & Utilities | |
 | Smoochies Chunk | A chunk of holiday chocolate used to craft wonderfully thematic items. | Consumables | 2 |
 | Smoothie Station | Mixes n' blends things into a drinkable substance that restores health or provides various side effects. | Building & Utilities | |
 | Snackbar Anthill | The entrance to an inconspicuous anthill under the snackbar—the home of a small red ant colony. | Key Items | |
 | Snackbar TURBO Optical Disk | Contains recipes! Load it into a Ranger Station and use the Science Shop to access them. | Key Items | |
 | Snail Jerky | Chewy strips of dried and preserved garden snail meat. No risk of spoiling. | Consumables | 2 |
 | Snail Roast | A plump slab of roasted garden snail meat. Restores a large amount of hunger. | Consumables | 2 |
 | Snail Shell Casque | A tough and sturdy helmet to protect your noggin. Melee attacks generate more threat. | Armor | 3 |
 | Snail Shell Greaves | A set of greaves made with garden snail shells. Protection fighters can rely on. | Armor | 3 |
 | Snail Shell Plastron | Exceptional chestplate for fighters made from garden snail shells. | Armor | 3 |
 | Snake Scale | A scale plucked from a garter snake. Harness the power of life and death with this colorful scale. | Materials | 3 |
| Snapped Mallet | A beautiful wood-carved croquet mallet ruined by some sore loser. What a shame... | Key Items | |
 | Soda Drop | Old and sticky, but still moderately restores your thirst. | Consumables | 0 |
 | Soggy Journal | July 16th, 1992
I’m starting to think these journal entries are useless, no matter what the Wellness Officer says. No peace of mind can be had living inside of a corporate machine. I am just as much a product as the devices I invent.
July 20th, 1992
I dragged myself to a BBQ over the weekend. Sharon and Jeremy asked me how it was going. I hope they don’t actually try to apply for a job here. They’ll find out pretty fast that everything I’ve ever told them is a lie.
July 24th, 1992
I’ve decided to give it a month. If I don’t land on a project worthy of scientific inquiry, I’m quitting for good. There are other companies out there that respect their employees. Right? There must be. Somewhere.
August 17th, 1992
Just as I was about to quit, something interesting finally landed on my desk. I don’t think Patricia will like me eloping like this, but it could be what I’ve needed all along. I am not a number. I am not an employee. I am a man of science! | Key Items | |
 | Sour Arrow | A simple arrow that deals sour damage and tang on hit. | Ammo & Throwables | 3 |
 | Sour Glob | A collection of sour shards, baked and formed into a cubular glob. Perfect for imbuing equipment with special properties. | Materials | 2 |
 | Sour Katanga | Pucker foes with this finely crafted tangy blade. The mysterious stranger mastered the technique of folding sour globs into a deadly katana. | Weapons | 3 |
 | Sour Lump | A mouth-puckering lump from a sour candy. | Consumables | 3 |
 | Sour Sensation | Your taste buds have conquered the tangiest of flavors, granting tang resistance to your skin cells. | Mutations | |
 | Spectacular Spicy Shard | A condensed nugget of elemental force. Simply holding it fills you with power. | Trinkets | 2 |
 | Speed Droplet | A mystical droplet that gives you the energy to run faster and longer. (Playground Exclusive) | Trinkets | 3 |
 | Spicy Arrow | An arrow that deals spicy damage and sizzle on hit. | Ammo & Throwables | 2 |
 | Spicy Coaltana | Sear foes with a finely crafted blade, hammered out of tempered spicy globs and always-hot EverChar coal chunks. | Weapons | 3 |
 | Spicy Glob | A collection of spicy shards, baked and shaped into a cubular glob. Perfect for imbuing equipment with special properties. | Materials | 2 |
 | Spicy Safety | Spicy sediment seeps into your bloodstream. The fiery fragments protect you from the chill. | Mutations | |
| Spicy Shard | A fiery splinter from a spicy candy. | Consumables | 2 |
 | Spider Bait | An alluring blend of gnat bits to attract spiders. | Ammo & Throwables | 1 |
 | Spider Candle | A stationary light source that illuminates the area around it. | Building & Utilities | |
 | Spider Cider | A fizzy beverage with a pungent aftertaste. Drinking this helps you traverse webs safely. | Consumables | 0 |
| Spider Den Anthill: North Entrance | The northern entrance to a large anthill. But judging from the webs and egg sacs, it hasn't been home to ants for some time. | Key Items | |
| Spider Den Anthill: South Entrance | The southern entrance to a large anthill. But judging from the webs and egg sacs, it hasn't been home to ants for some time. | Key Items | |
 | Spider Den Optical Disk | Contains recipes! Load it into a Ranger Station and use the Science Shop to access them. | Key Items | |
 | Spider Nest | A cozy nest for your pet spider. Hatch spider eggs here to raise your own orb weaver. | Buggies | |
| Spider Nest | A relaxing home for your tamed spiders to unwind. | Building & Utilities | |
 | Spider Slider | A delicious burger made of various chunks of cooked spider. Hearty enough to be considered a whole meal. | Consumables | 2 |
 | Spider Stringer | A high quality bow made of sinewy orb weaver chunks. | Weapons | 2 |
